Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer
Searching the Database
The information in the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer relates chromosomal aberrations to tumor characteristics, based either on individual cases or associations. All the data have been manually culled from the literature by Felix Mitelman, Bertil Johansson, and Fredrik Mertens.
CGAP has developed six web search tools to help you analyze the information within the Mitelman Database:
- The Cases Quick Searcher allows you to query the individual patient cases using the four major fields: aberration, breakpoint, morphology, and topography.
- The Cases Full Searcher permits a more detailed search of the same individual patient cases as above, by including more cytogenetic field choices and adding search fields for patient characteristics and references.
- The Molecular Biology Associations Searcher does not search any of the individual patient cases. It searches studies pertaining to gene rearrangements as a consequence of cytogenetic aberrations.
- The Clinical Associations Searcher does not search any of the individual patient cases. It searches studies pertaining to clinical associations of cytogenetic aberrations and/or gene rearrangements.
- The Recurrent Chromosome Aberrations Searcher provides a way to search for structural and numerical abnormalities that are recurrent, i.e., present in two or more cases with the same morphology and topography.
- The Reference Searcher queries only the references themselves, i.e., the references from the individual cases and the molecular biology and clinical associations.
Database last updated on November 11, 2015
Total number of cases = 66,234
Total number of gene fusions = 10,180
Need help! To learn about the Mitelman Database and how to search it, please visit:
- All about the Mitelman Database, which provides background information about the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer.
- Mitelman Database Search Help, which contains information on how to use the search tools.
- ISCN Abbreviated Terms and Symbols, which provides a list of terms and symbols used to describe chromosome abnormalities.
Citation of the Database
To cite the use of the Mitelman Database from this CGAP Website in a publication, please quote the following: "Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (2016). Mitelman F, Johansson B and Mertens F (Eds.), http://cgap.nci.nih.gov/Chromosomes/Mitelman"
The Mitelman Database is supported by the Swedish Cancer Society and the Swedish Childhood Cancer Foundation. The database is updated quarterly in February, May, August, and November.