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The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
9p21 inv(9)(p21q22) Acute myeloid leukemia, NOS    
9p21 t(2;9)(q14;p21) Multiple myeloma    
9p21 t(3;8;9)(p21;q12;p21) Adenoma Salivary gland PLAG1+
9p21 t(9;11)(p21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   MLL/MLLT3
9p21 t(9;11)(p21;q23) Acute megakaryoblastic leukemia (FAB type M7)   MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute monoblastic leukemia (FAB type M5)   54  MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute monoblastic leukemia with differentiation (FAB type M5b)   MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute monoblastic leukemia without differentiation (FAB type M5a)   31  MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute myeloblastic leukemia with maturation (FAB type M2)    
9p21 t(9;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute myeloblastic leukemia without maturation (FAB type M1)   MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute myeloid leukemia, NOS   MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Acute myelomonocytic leukemia (FAB type M4)   19  MLL/MLLT3,MLL+
9p21 t(9;11)(p21;q23) Bilineage or biphenotypic leukemia   MLL+
9p21 t(9;12)(p21;p12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 t(9;13)(p21;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 t(9;14)(p21;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   TRA/CDKN2A,TRD+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
9p21 add(9)(p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   16   
9p21 add(9)(p21) Acute myeloid leukemia, NOS    
9p21 add(9)(p21) Adenocarcinoma Pancreas  
9p21 add(9)(p21) Adenocarcinoma Breast  
9p21 add(9)(p21) Astrocytoma, grade III-IV Brain  
9p21 add(9)(p21) Chronic lymphocytic leukemia    
9p21 add(9)(p21) Diffuse large B-cell lymphoma    
9p21 add(9)(p21) Follicular lymphoma    
9p21 add(9)(p21) Hodgkin disease, mixed cellularity    
9p21 add(9)(p21) Mantle cell lymphoma    
9p21 add(9)(p21) Mature B-cell neoplasm, NOS    
9p21 add(9)(p21) Mesothelioma Pleura  
9p21 add(9)(p21) Multiple myeloma    
9p21 add(9)(p21) Refractory anemia with excess of blasts (FAB)    
9p21 del(9)(p11p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 del(9)(p13p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 del(9)(p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   127   
9p21 del(9)(p21) Acute megakaryoblastic leukemia (FAB type M7)    
9p21 del(9)(p21) Acute myeloblastic leukemia with maturation (FAB type M2)    
9p21 del(9)(p21) Acute myeloblastic leukemia without maturation (FAB type M1)    
9p21 del(9)(p21) Acute myeloid leukemia, NOS    
9p21 del(9)(p21) Acute myelomonocytic leukemia (FAB type M4)    
9p21 del(9)(p21) Adenocarcinoma Large intestine  
9p21 del(9)(p21) Adenocarcinoma Lung  
9p21 del(9)(p21) Adenocarcinoma Kidney  
9p21 del(9)(p21) Adenocarcinoma Breast  
9p21 del(9)(p21) Astrocytoma, grade III-IV Brain 15   
9p21 del(9)(p21) Burkitt lymphoma/leukemia    
9p21 del(9)(p21) Chronic lymphocytic leukemia    
9p21 del(9)(p21) Chronic myeloid leukemia, t(9;22)    
9p21 del(9)(p21) Diffuse large B-cell lymphoma    
9p21 del(9)(p21) Ewing sarcoma Skeleton  
9p21 del(9)(p21) Follicular lymphoma    
9p21 del(9)(p21) Malignant melanoma Skin  
9p21 del(9)(p21) Mature B-cell neoplasm, NOS    
9p21 del(9)(p21) Mesothelioma Pleura  
9p21 del(9)(p21) Multiple myeloma    
9p21 del(9)(p21) Mycosis fungoides/Sezary syndrome    
9p21 del(9)(p21) Peripheral T-cell lymphoma, unspecified    
9p21 del(9)(p21) Splenic marginal zone B-cell lymphoma    
9p21 del(9)(p21) Squamous cell carcinoma Lung  
9p21 del(9)(p21p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   31   
9p21 del(9)(p21p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   31   
9p21 del(9)(p21p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 del(9)(p21p23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 del(9)(p21p24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 der(17)t(9;17)(p21;p13) Diffuse large B-cell lymphoma    
9p21 der(9)del(9)(p21)t(9;22)(q34;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
9p21 der(9)t(9;11)(p21;q23) Acute monoblastic leukemia (FAB type M5)    
9p21 der(9)t(9;12)(p21;q13) Follicular lymphoma